Description
Tirzepatide (10mg) | GIP/GLP-1 Dual Agonist — Metabolic Research Peptide
Tirzepatide is the active ingredient in FDA-approved Mounjaro (type 2 diabetes) and Zepbound (obesity), representing the first clinically approved dual GIP/GLP-1 receptor agonist. As a 39-amino acid peptide, it demonstrates balanced agonism at both receptors with glucose-dependent insulin secretion. SURMOUNT-1 trial showed 22.5% mean body weight reduction. This 10mg lyophilised vial format supports injectable delivery research protocols and pharmacokinetic studies.
Mechanism of Action
- GLP-1R agonism — enhances glucose-dependent insulin secretion, suppresses glucagon, delays gastric emptying, and reduces appetite
- GIPR agonism — amplifies insulin secretion additively; CNS-expressed GIPR mediates independent weight loss effects
- Beta-cell function — preclinical and clinical data indicate improved beta-cell mass preservation over time
- Lipid metabolism — reduces hepatic fat content and improves adipose tissue lipolytic activity
Research Areas
Tirzepatide is studied in type 2 diabetes, obesity, NASH, cardiac outcomes, and incretin biology. Compare with Retatrutide (adding glucagon receptor) and Cagrilintide (amylin agonist) for mechanistic pathway comparisons.
For Research Use Only. Rainbow Peptide supplies this compound exclusively for in vitro and laboratory research purposes. Not for human or veterinary use.
Dr. M. Vasquez –
Tirzepatide for our GLP-1/GIP dual agonist study. Purity confirmed at 98.9% by our HPLC. The dual incretin receptor activity in our cell-based assay matched published reference data. COA was the most detailed we’ve seen.
R. Johansson –
Third order of Tirzepatide for our obesity research panel. Consistent purity above 98.5% across all lots. Cold-chain delivery intact on arrival. COA includes both HPLC and mass spec — our compliance team was satisfied.
A. Osei –
Good Tirzepatide. Purity verified at 98.4% independently. Dissolved in bacteriostatic water cleanly. COA was comprehensive. Shipping was fast with appropriate cold packaging.