Description
GHK-Cu | Copper Peptide Gly-His-Lys — Research Grade
GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Cu2+) is an endogenous tripeptide-copper complex first isolated from human plasma albumin. It has been studied across more than four decades of research, with a uniquely broad biological profile spanning tissue remodelling, antioxidant activity, and gene expression.
Mechanism of Action
- Collagen and elastin synthesis — upregulates Type I/III collagen, elastin, fibronectin, and GAG production in fibroblast cultures
- MMP modulation — simultaneously increases MMP-2 (remodelling) while inducing TIMP-1/2 (anti-degradation)
- Gene expression — studies indicate GHK modulates up to 32% of the human genome, including pathways related to inflammation, cell proliferation, and oxidative stress
- Antioxidant copper chelation — the Cu2+ complex confers SOD-like activity and protects cells from oxidative DNA damage
Research Areas
GHK-Cu is studied in wound healing, skin ageing, hair follicle biology, pulmonary fibrosis (TGF-beta1 inhibition), and neurodegeneration.
For Research Use Only. Rainbow Peptide supplies GHK-Cu exclusively for in vitro and laboratory research purposes. Not for human or veterinary use.
Dr. M. Vasquez –
GHK-Cu used in our dermal fibroblast collagen synthesis research. This lot had >98% purity by HPLC — COA cited reference standard lot number, which is a rare level of traceability. Results in our assay were exactly as expected.
N. Ferrara –
Best GHK-Cu sourcing this quarter. Sourced from three vendors and Rainbow Peptide had the most detailed COA and lowest endotoxin levels. In vitro wound healing assay showed the expected MMP modulation. Will be primary source.
H. Brennan –
GHK-Cu arrived in 2 days. Cold pack active. Dissolved cleanly in saline. COA comprehensive. Our collagen gel contraction assay showed expected activity. Good value for a research-grade tripeptide-copper complex.