Description
Argireline | Acetyl Hexapeptide-3, Research Grade
Argireline (Acetyl Hexapeptide-3; Ac-EEMQRR-NH2) is a synthetic hexapeptide designed to mimic the N-terminal sequence of SNAP-25, a key component of the SNARE complex. It has been extensively studied in cosmetic dermatology and neuromuscular junction biology.
Mechanism of Action
- SNARE complex competition, competes with SNAP-25 for binding sites in the SNARE complex, reducing vesicle docking efficiency
- Neurotransmitter release inhibition, reduces acetylcholine release at neuromuscular junctions in cell-based models
- VAMP inhibition, interacts with vesicle-associated membrane protein, attenuating exocytosis
Research Areas
Argireline is studied in neuromuscular junction biology, cosmetic skin research (wrinkle formation), SNARE biology, and exocytosis pathway research.
Independent Lab Verification
Rainbow Peptide works with independent, accredited third-party laboratories, including Vanguard Laboratory (ISO 17025:2017-accredited, A2LA Certificate #6377.01.01), to verify compound identity and purity. A Certificate of Analysis is included with every order.
For Research Use Only. Rainbow Peptide supplies Argireline exclusively for in vitro and laboratory research purposes. Not for human or veterinary use.
Dr. C. Blanes –
Argireline (Acetyl Hexapeptide-3) for our SNAP-25 inhibition and wrinkle-reduction mechanism research. Purity confirmed >99% by HPLC. Neuromuscular junction assay showed expected acetylcholine release inhibition.
I. Gustafsson –
High purity Argireline for our dermatological peptide research. COA confirms >99% with full HPLC trace. Dissolved cleanly in water. Our SNAP-23/25 binding assay showed the expected Botulinum-like mechanism.
B. Kamara –
Argireline for cosmeceutical ingredient research. Purity >98.5%. COA thorough. Dissolved easily. Our in vitro muscle relaxation model showed the expected hexapeptide activity. Good quality for the price.